Procaine dosage and interaction with gallamine in children.

The dose of procaine (in mg/kg/min) necessary to obtain a satisfactory light level of general anaesthesia in children from 18 to 168 months old, diminishes with increasing age. There is no difference in the procaine requirement between sexes. When higher doses of procaine are injected, greater amounts of gallamine are needed to maintain satisfactory relaxation. Young children require higher doses of gallamine than the older ones. A curvilinear regression has been constructed so that mg/kg/min doses of procaine in relation to sex and age can easily be found.